What is Cardarine GW501516?

What's the Cardarine GW501516?

GW501516 also known as GW1516, GW501, GW516 belongs to a family of drugs that act on the peroxisome proliferator-activated receptor (PPAR agonist). Most commonly known as Cardarine or Endurobol, it is an oral, bioactive drug that interacts directly with cell tissues.

PPAR agonists were originally designed to help reduce triglycerides and blood sugar levels. Cardarine GW1516 was developed in a collaboration of GlaxoSmithKline and Ligand Pharmaceuticals. Ligand went on to develop LGD4033 (Ligandrol), an oral selective androgen receptor modulator (SARM) for treating muscle wasting and osteoporosis.

How dose Cardarine works ?

Although Cardarine has previously been referred to as a SARM (selective androgen receptor modulator), it is not. SARMs were first developed in the 1940s to mimic testosterone. They work by activating the androgen receptors in specific tissues such as bone and muscle, which causes an increase in muscle mass.
Cardarine works by activating AMP-activated protein kinase, glucose uptake, and fatty acid oxidation in skeletal muscle. In this way, it can reverse metabolic abnormalities in obese and pre-diabetic individuals by stimulating fatty acid oxidation, burning fat, and increasing glucose uptake in skeletal muscle tissue, which changes the body’s metabolism to burn fat for energy instead of muscle or carbohydrates.

In other words, Cardarine forces skeletal muscle to use fat rather than carbohydrates as an energy source. It’s said to boost stamina, endurance, workout capacity, and fat loss within just days of usage, particularly for overweight or unfit athletes.

This has made it highly desirable for athletes seeking to enhance their endurance or to boost fat loss. Like other PPARs, Cardarine has a significant effect on endurance, allowing the user to push harder and longer without becoming fatigued.

How to use the cardarine?

According to most users’ reports found online, the most effective cardarine GW501516 dosage is between 10 to 20mg per day. One should take full dosage one to two hours before exercising.

Other suppliers recommend starting with 10 mg Cardarine/Endurobol per day to boost endurance, while higher dosages promote greater fat loss.

Cardarine’s half-life is about 24 hours, so a single intake daily is usually sufficient. Those who wish to split the dose can take one morning and one evening. Cardarine is best taken 45 minutes to 1 hour before training. In most cases, a cycle will last from around 4 to 8 weeks, and the maximum application cycle is 12-14 weeks.

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